NSAID Use Increase Future Risk of Stroke and MI

Recent large retrospective study of 500,000 Danish healthy adults found in the Danish national medical registries reveals that use of Non-Steroidal Anti-Inflammatories, NSAIDs, (medications like ibuprofen, Naproxen sodium, and diclofenac) increase risk of future stroke.  Populations were controlled for age, gender, socioeconomic status, and patients with chronic disease were excluded.  The risk of stroke was found to be dose dependent with increased risk with increasing frequency of the use of NSAIDs.

Until further information is available about why this risk occurs in healthy patients, be cautious with the amount and frequency of NSAID use.